I'm surprised by the five-star rating. This movie has nothing to offer adults. And I'm quite positive I would have disliked it even as a kid. The humor is imbecilic and immature.
A couple of disclaimers: I only made it 20 minutes in (I really wanted to like it, but I couldn't bear to watch more). Also, I haven't seen any of the other Pee-Wee Herman movies.
I've seen Starship Troopers... I can handle "campy". I've seen the Austin Powers moves... I can handle "immature" humor. But this movie was just too much. There were funny, quirky parts that were interesting, but it wasn't enough to redeem the rest. And the story-line (so far) just seemed random and vague, like stream of consciousness.
I would recommend this movie for someone under the age of 10 who has seen the other (supposedly better?) Peewee Herman movies and who hasn't yet discovered better quality movies ;) Sorry, I really didn't like it. Would not recommend to anyone I know. And I probably won't be watching the other Peewee Herman movies, based on what I saw in this one.