These Gonex Compression Packing Cubes - Extensible Storage Mesh Bags Organizers were the winner!
We traveled for two weeks in Italy and used only carry on backpack bags. I have never used cubes of any kind, but this time, since we were travelling light, I purchased these Gonex compression cubes along with some Spacesaver vacuum bags and some regular Gonex non-compression packing cubes. We left the vacuum bags at home after we decided that they (with the pump) were too much of a hassle. I brought one or two non-compression cubes and one was used by my son to carry his books and games.
I was able to use the large back for my pants/jeans and extra jacket and a sweater. The medium was used for my tops and the smaller ones for underwear and socks. I had a larger laundry bag and this laundry bag is more the size of a shoe bag so that's how I used it.
I like how you can use the compression zipper for packing, but then use it like a normal cube for dresser drawers. In the end, since we were hand washing along the way, I ended up not using them for clean and dirty clothes for the way home and thought maybe I should have brought along one or two of the vacuum bags to separate the clean and dirty clothes on the way home. I ended up mixing and doing one big wash of all in the end.
I would definitely buy these again for another trip like this.